Recombinant Human TSSK2 Protein (RMPP-00230427)
Cat. No.: RMPP-00230427
Category: Recombinant Protein
Research Area: Stem Cells
INQUIRY
10 μg
5 μg
Product Features
| Source | HEK 293 cells |
|---|---|
| Purity | > 98% SDS-PAGE. Purity: > 98% by SDS-PAGE and HPLC analysis. |
| Nature | Recombinant |
| Animal Free | No |
| Form | Lyophilized |
| Applications | Functional Studies; SDS-PAGE; HPLC |
| Key Features | Expression system: HEK 293 cells; Purity: > 98% SDS-PAGE; Active: Yes; Suitable for: Functional Studies, SDS-PAGE, HPLC |
Protein Information
| UniProt ID | O00755 |
|---|---|
| Molecular Weight | 36 kDa |
| Sequence Similarities | Belongs to the Wnt family. |
| Protein Length | Full length protein |
| Cellular Localization | Secreted > extracellular space > extracellular matrix. |
| Tissue Specificity | Expression is restricted to placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain. |
| Function | Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. Signaling by Wnt-7a allows sexually dimorphic development of the mullerian ducts. |
| Involvement in Disease | Defects in WNT7A are the cause of limb/pelvis-hypoplasia/aplasia syndrome (LPHAS); also known as absence of ulna and fibula with severe limb deficiency. LPHAS is a limb-malformation disorder characterized by various degrees of limb aplasia/hypoplasia and joint dysplasia.Defects in WNT7A are a cause of Fuhrmann syndrome (FUHRS); also known as fibular aplasia or hypoplasia femoral bowing and poly- syn- and oligodactyly. Fuhrmann syndrome is a distinct limb-malformation disorder characterized also by various degrees of limb aplasia/hypoplasia and joint dysplasia. |
Storage & Shipping
| Shipping and Storage | Shipped at 4°C. Store at -20°C. Store under desiccating conditions. This product is an active protein and may elicit a biological response in vivo, handle with caution. |
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For research use only. Not for clinical use.
