Anti-delta 1 Catenin/p120 Catenin Rabbit Monoclonal Antibody (RMAB-0251406)
Cat. No.: RMAB-0251406
Category: Primary Antibodies
Research Area: Stem Cells
INQUIRY
100 μL
Customer Size
Anti-delta 1 Catenin/p120 Catenin Rabbit Monoclonal Antibody. Tested in IP, IF, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Features
| Isotype | IgG |
|---|---|
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Form | Liquid |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide corresponding to Human delta 1 Catenin/CAS (phospho S268). |
| Applications | WB, Flow Cyt |
Target Information
| Target Symbol | CTNND1 |
|---|---|
| Target Name | Catenin delta-1 |
| UniProt ID | O60716 |
| Function | Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. |
| Post-translational Modifications | Phosphorylated by protein-tyrosine kinases. Dephosphorylated by PTPRJ. |
| Domain | A possible nuclear localization signal exists in all isoforms where Asp-626--631-Arg are deleted. |
| Sequence Similarities | Belongs to the beta-catenin family. Contains 1 ARM repeats. |
Storage & Shipping
| Storage Buffer | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
|---|---|
| Storage & Shipping | Dry Ice |
For research use only. Not for clinical use.
