Defactinib, FAK inhibitor (RMML-00120754)
Cat. No.: RMML-00120754
Category: Inhibitors & Activators
INQUIRY
5 mg
25 mg
Potent FAK inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Potent FAK inhibitor; CAS Number: 1073154-85-4; Purity: > 98%; Soluble in DMSO to 25 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | FAK |
|---|---|
| Biological Description | Potent FAK inhibitor. Prevents tumor invasion and dissemination. Preferentially targets cancer stem cells in mouse xenograft models. Orally bioavailable. |
| Alternative Names | PF-04554878, VS-6063 |
| CAS Number | 1073154-85-4 |
| Chemical Name | N-Methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamide |
| SMILES | CNC(=O)C1=CC=C(C=C1)NC2=NC=C(C(=N2)NCC3=NC=CN=C3N(C)S(=O)(=O)C)C(F)(F)F |
| Molecular Formula | C20H21F3N8O3S |
| Molecular Weight | 510.49 Da |
| PubChem Identifier | 25117126 |
Storage & Shipping
| Handling | Refer to SDS for further information. |
|---|---|
| Solubility | Soluble in DMSO to 25 mM |
| Storage & Shipping | Shipped at room temperature. Store at -20°C. Store under desiccating conditions. |
For research use only. Not for clinical use.
