SB431542, ALK inhibitor (RMML-00120082)
Cat. No.: RMML-00120082
Category: Inhibitors & Activators
INQUIRY
10 mg
5 mg
ALK inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Key Features | ALK inhibitor; CAS Number: 301836-41-9; Soluble in DMSO to 100 mM and in ethanol to 10 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | ALK |
|---|---|
| Biological Description | Potent and selective inhibitor of Activin Like Kinase. Inhibits ALK 4, 5 (IC50 = 94 nM), and 7. 3D Growth matrix component; also component of brain and blood vessel organoid differentiation media. |
| CAS Number | 301836-41-9 |
| Chemical Name | 4-[4-(3,4-Methylenedioxyphenyl)-5-(2-pyridyl)-1H-imidazol-2-yl]benzamide |
| SMILES | NC(=O)c1ccc(cc1)c3nc(c2ccccn2)c(n3)c4ccc5OCOc5c4 |
| Molecular Formula | C22H16N4O3 |
| Molecular Weight | 384.39 Da |
| PubChem Identifier | 4521392 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO to 100 mM and in ethanol to 10 mM |
| Storage & Shipping | Store at room temperature. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
