Ro 31-8220 mesylate (Bisindolylmaleimide IX), Protein kinase inhibitor (RMML-00120847)
Cat. No.: RMML-00120847
Category: Inhibitors & Activators
INQUIRY
1 mg
10 mg
Protein kinase inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Protein kinase inhibitor; CAS Number: 138489-18-6; Purity: > 98%; Soluble in DMSO and organic solvents. Solubility in these solvents is approximately 20 mg/mL.; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | Protein kinase |
|---|---|
| Biological Description | Widely used as a cell-permeable, reversible, competitive protein kinase C inhibitor. Also potently inhibits wide range of kinases inlcuding RSK1, RSK2, PRK2, PKCα, PKD1, MSK1, GSK3β, CDK2-cyclin A and PIM3, as well as PKCα.Also available in simple stock solutions (ab146723) - add 1 mL of water to get an exact, ready-to-use concentration. |
| Alternative Names | Bisindolylmaleimide IX |
| CAS Number | 138489-18-6 |
| Chemical Name | 3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione methanesulfonate |
| SMILES | CS(=O)(=O)O.Cn2cc(c1ccccc12)C=5C(=O)NC(=O)C=5c4cn(CCCSC(=N)N)c3ccccc34 |
| Molecular Weight | 553.65 Da |
| PubChem Identifier | 11628205 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in DMSO and organic solvents. Solubility in these solvents is approximately 20 mg/mL. |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
