SC-1 (Pluripotin), Dual kinase and GTPase inhibitor (RMML-00120236)
Cat. No.: RMML-00120236
Category: Inhibitors & Activators
INQUIRY
25 mg
10 mg
Dual kinase (ERK1, MAPK3) and GTPase inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Dual kinase (ERK1, MAPK3) and GTPase inhibitor; CAS Number: 839707-37-8; Purity: > 98%; Soluble in DMSO to 25 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | Dual kinase, GTPase |
|---|---|
| Biological Description | Dual kinase (ERK1, MAPK3) and GTPase inhibitor. Activates stem cell renewal. Enables propagation of undifferentiated murine ESCs in the absence of leukemia inhibitory factor. |
| CAS Number | 839707-37-8 |
| Chemical Name | N-(3-(7-(1,3-Dimethyl-1H-pyrazol-5-ylamino)-1-methyl-2-oxo-1,2-dihydropyrimido[4,5-d]pyrimidin-3(4H)-yl)-4-methylphenyl)-3-(trifluoromethyl)benzamide |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)N3CC4=CN=C(N=C4N(C3=O)C)NC5=CC(=NN5C)C |
| Molecular Formula | C27H25F3N8O2 |
| Molecular Weight | 550.54 Da |
| PubChem Identifier | 12003241 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. |
|---|---|
| Solubility | Soluble in DMSO to 25 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
