Erastin, ferroptosis activator (RMML-00120920)
Cat. No.: RMML-00120920
Category: Inhibitors & Activators
INQUIRY
1 mg
5 mg
Selective ferroptosis activator
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Selective ferroptosis activator; CAS Number: 571203-78-6; Purity: > 98%; Soluble in DMSO to 20 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | ferroptosis |
|---|---|
| Biological Description | Selective ferroptosis activator. Induces RAS-RAF-MEK-dependent non-apoptotic cell death via VDAC2 (IC50 = 0.1 μM). |
| CAS Number | 571203-78-6 |
| Chemical Name | 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone |
| SMILES | CCOC1=CC=CC=C1N2C(=O)C3=CC=CC=C3N=C2C(C)N4CCN(CC4)C(=O)COC5=CC=C(C=C5)Cl |
| Molecular Formula | C30H31ClN4O4 |
| Molecular Weight | 547.04 Da |
| PubChem Identifier | 11214940 |
Storage & Shipping
| Handling | Toxic, refer to SDS for further information. |
|---|---|
| Solubility | Soluble in DMSO to 20 mM |
| Storage & Shipping | Shipped at 4°C. Store at -20°C long term. It is important to note that this product is reported to be light sensitive. Store under desiccating conditions. |
For research use only. Not for clinical use.
