Human CD19 Protein (Active) (Biotin) (RMPP-00230153)
Cat. No.: RMPP-00230153
Category: Native Protein
Research Area: Cardiovascular
INQUIRY
25 μg
200 μg
Product Features
| Source | Native |
|---|---|
| Nature | Native |
| Animal Free | No |
| Conjugation | Rhodamine |
| Form | Lyophilized |
| Applications | Flow Cytometry; IM |
| Key Features | Expression system: Native; Suitable for: Flow Cyt, Immunomicroscopy |
Protein Information
| UniProt ID | P02768 |
|---|---|
| Molecular Weight | 69 kDa |
| Sequence Similarities | Belongs to the ALB/AFP/VDB family. Contains 3 albumin domains. |
| Protein Length | Full length protein |
| Cellular Localization | Secreted. |
| Tissue Specificity | Plasma. |
| Function | Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc. |
| Involvement in Disease | Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH). FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population. |
| Post-translational Modifications | Kenitra variant is partially O-glycosylated at Thr-620. It has two new disulfide bonds Cys-600 to Cys-602 and Cys-601 to Cys-606.Glycated in diabetic patients.Phosphorylation sites are present in the extracelllular medium.Acetylated on Lys-223 by acetylsalicylic acid. |
Storage & Shipping
| Shipping and Storage | Shipped at 4°C. Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C. Avoid freeze / thaw cycle. Preservative: 0.01% Sodium azideConstituents: 0.42% Potassium phosphate, 0.87% Sodium chloride, 1% BSA |
|---|
For research use only. Not for clinical use.