LM11A-31, nonpeptide p75NTR ligand (RMML-00120926)
Cat. No.: RMML-00120926
Category: Inhibitors & Activators
INQUIRY
25 mg
5 mg
Selective nonpeptide p75NTR ligand
Product Features
| Source | Synthetic |
|---|---|
| Key Features | Selective nonpeptide p75; NTR; ligand; CAS Number: 1243259-19-9; Soluble in water to 100 mM and in DMSO to 100 mM; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | nonpeptide p75NTR |
|---|---|
| Biological Description | Selective nonpeptide p75NTR ligand. Blocks p75-mediated cell death. Promotes neurogenesis and neurite survival. Does not affect NGF binding to TrkA. Shows neuroprotective and neuroregenerative effects in vivo. Orally active. Blood-brain barrier permeable. |
| CAS Number | 1243259-19-9 |
| Chemical Name | (2S,3S)-2-Amino-3-methyl-N-(2-morpholin-4-ylethyl)pentanamide dihydrochloride |
| SMILES | CC[C@H](C)[C@@H](C(=O)NCCN1CCOCC1)N.Cl.Cl |
| Molecular Formula | C12H25N3O2.2HCl |
| Molecular Weight | 316.27 Da |
| PubChem Identifier | 91654620 |
Storage & Shipping
| Handling | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. |
|---|---|
| Solubility | Soluble in water to 100 mM and in DMSO to 100 mM |
| Storage & Shipping | Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
For research use only. Not for clinical use.
