PF-04965842 (Abrocitinib) (RMML-00120816)
Cat. No.: RMML-00120816
Category: Inhibitors & Activators
INQUIRY
5 mg
Potent, selective JAK1 inhibitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | ≥ 98% |
| Key Features | Potent, selective JAK1 inhibitor; CAS Number: 1622902-68-4; Purity: ≥ 98%; >10 mg/mL DMSO; Form / State: Solid; Source: Synthetic |
Compound Information
| Biological Description | Potent, selective, orally bioavailable JAK1 inhibitor (IC50 = 29 nM). It displays excellent selectivity for JAK1 versus other JAK family enzymes. |
|---|---|
| Alternative Names | Abrocitinib |
| CAS Number | 1622902-68-4 |
| Chemical Name | N-[3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl]propane-1-sulfonamide |
| SMILES | CCCS(=O)(=O)NC1CC(C1)N(C)C2=NC=NC3=C2C=CN3 |
| Molecular Formula | C14H21N5O2S |
| Molecular Weight | 323.42 Da |
| PubChem Identifier | 78323835 |
Storage & Shipping
| Handling | Toxic, refer to SDS for further information. |
|---|---|
| Solubility | >10 mg/mL DMSO |
| Storage & Shipping | Shipped at 4°C. Store at -20°C. |
For research use only. Not for clinical use.
