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CFTR(inh)-172 (RMML-00120186)

Cat. No.: RMML-00120186

Category: Inhibitors & Activators

INQUIRY 1 mg 5 mg
CFTR(inh)-172 is a selective and reversible thiazolidinone inhibitor of the cystic fibrosis transmembrane conductance regulator. CFTR is a chloride anion channel involved in the secretion of fluid in many epithelial tissues, such as the airway and intestine. Defects in the CFTR gene alter ion transport, which can lead to cystic fibrosis. When it is intraperitoneally injected in mice, CFTR(inh)-172 inhibits the secretion of intestinal fluid induced by cholera toxin. Slows cyst growth in polycystic kidney disease in mice.

Product Features

Purity ≥ 98%

Compound Information

Alternative Names Cystic fibrosis transmembrane conductance regulator inhibitor 172, CFTR Inhibitor-172
CAS Number 307510-92-5
Molecular Formula C18H10F3NO3S2
Molecular Weight 409.4 Da

Storage & Shipping

Handling Refer to SDS for further information.

For research use only. Not for clinical use.