Recombinant Human WISP2 Protein (RMPP-00230422)
Cat. No.: RMPP-00230422
Category: Growth Factors & Cytokines
Research Area: Signal Transduction
INQUIRY
20 μg
5 μg
Product Features
| Source | E.coli |
|---|---|
| Purity | > 98% SDS-PAGE. > 98% HPLC. |
| Nature | Recombinant |
| Animal Free | Yes |
| Form | Lyophilized |
| Applications | Functional Studies; SDS-PAGE; HPLC |
| Key Features | Expression system: E.coli; Purity: > 98% SDS-PAGE; Active: Yes; Suitable for: Functional Studies, SDS-PAGE, HPLC |
Protein Information
| UniProt ID | P10600 |
|---|---|
| Molecular Weight | 25 kDa |
| Sequence | ALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPY LRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKVEQ LSNMVVKSCKCS |
| Sequence Similarities | Belongs to the TGF-beta family. |
| Protein Length | Full length protein |
| Cellular Localization | Secreted. |
| Function | Involved in embryogenesis and cell differentiation. |
| Involvement in Disease | Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1); also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall. |
Storage & Shipping
| Shipping and Storage | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. This product is an active protein and may elicit a biological response in vivo, handle with caution. |
|---|
For research use only. Not for clinical use.
