Recombinant Mouse CD62L Protein (RMPP-00230902)
Cat. No.: RMPP-00230902
Category: Recombinant Protein
Research Area: Neuroscience
INQUIRY
20 μg
Customer Size
Product Features
| Source | E.coli |
|---|---|
| Purity | > 95% SDS-PAGE. Purity was determined to be >95% by densitometry. |
| Nature | Recombinant |
| Animal Free | No |
| Form | Liquid |
| Applications | SDS-PAGE; WB |
| Key Features | Expression system: E.coli; Purity: > 95% SDS-PAGE; Suitable for: SDS-PAGE, WB |
Protein Information
| UniProt ID | P31947 |
|---|---|
| Sequence Similarities | Belongs to the 14-3-3 family. |
| Protein Length | Full length protein |
| Cellular Localization | Cytoplasm. Nucleus. Secreted. May be secreted by a non-classical secretory pathway. |
| Tissue Specificity | Present mainly in tissues enriched in stratified squamous keratinizing epithelium. |
| Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.p53-regulated inhibitor of G2/M progression. |
| Post-translational Modifications | Ubiquitinated. Ubiquitination by RFFL induces proteasomal degradation and indirectly regulates p53/TP53 activation. |
Storage & Shipping
| Shipping and Storage | Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles. pH: 7.50Constituents: 0.00174% PMSF, 0.00385% DTT, 0.79% Tris HCl, 25% Glycerol (glycerin, glycerine), 0.29% Sodium chloride |
|---|
For research use only. Not for clinical use.
