LMK 235, HDAC inhibitor (RMML-00120397)
Cat. No.: RMML-00120397
Category: Inhibitors & Activators
INQUIRY
25 mg
5 mg
Highly potent and selective HDAC inhbitor
Product Features
| Source | Synthetic |
|---|---|
| Purity | > 98% |
| Key Features | Highly potent and selective HDAC inhbitor; CAS Number: 1418033-25-6; Purity: > 98%; Soluble in DMSO; Form / State: Solid; Source: Synthetic |
Compound Information
| Target Pathways | HDAC |
|---|---|
| Biological Description | Highly potent and selective HDAC inhibitor. Greater potency for HDAC4 and HDAC5 (IC50 = 11.9 and 4.2 nM, respectively) than other HDAC family members (IC50 values = HDAC1 320 nM, HDAC2 881 nM, HDAC6 55.7 nM, and HDAC8 1278 nM. Demonstrates inhibitor activity in human ovarian cell lines (IC50 =0.49µM) and cisplatin resistant cell lines (IC50 = 0.32µM). |
| CAS Number | 1418033-25-6 |
| Chemical Name | N-[6-(Hydroxyamino)-6-oxohexoxy]-3,5-dimethylbenzamide |
| SMILES | CC1=CC(=CC(=C1)C(=O)NOCCCCCC(=O)NO)C |
| Molecular Formula | C15H22N2O4 |
| Molecular Weight | 294.35 Da |
| PubChem Identifier | 71520717 |
Storage & Shipping
| Handling | Refer to SDS for further information. |
|---|---|
| Solubility | Soluble in DMSO |
| Storage & Shipping | Shipped at 4°C. Store at -20°C long term. Store in the dark. |
For research use only. Not for clinical use.
